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Clinical trials

2615 results

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ProofPrinciple IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophageal Adenocarcinoma w/ARID1a In

Study ID: NCT06824363
Start Date: 2026-04
End Date: 2028-07
Study Type

Interventional

Study Phase

Early_phase1

No. of Participants

34

Intervention / Treatment

Tremelimumab

Durvalumab

Sponsor

University of California, Irvine

Source: clinicaltrials.gov

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Impact of Prehospital Stroke Care Patterns on Clinical Outcomes in Acute Stroke Patients

Study ID: NCT07198893
Start Date: 2026-10-01
End Date: 2027-12-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

125

Intervention / Treatment
Sponsor

Assiut University

Source: clinicaltrials.gov

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Comparing a Healthy Beef-Centric Diet to a Healthy U.S.-Style Diet on Metabolic Health Outcomes in Pre-Diabetic Adults

Study ID: NCT07269847
Start Date: 2026-02-03
End Date: 2026-06-18
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

56

Intervention / Treatment

Healthy Beef-Centric Diet

Healthy U.S.-Style Dietary Pattern

Sponsor

National Cattlemen's Beef Association, a contractor to the Beef Checkoff

Source: clinicaltrials.gov

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Dynamic Treatment Regimes for Opioid Use Disorder

Study ID: NCT07011758
Start Date: 2028-07-01
End Date: 2030-06-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

75

Intervention / Treatment

Medication for opioid use disorder

psychotherapy

Sponsor

Brigham and Women's Hospital

Source: clinicaltrials.gov

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Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting

Study ID: NCT07314138
Start Date: 2026-04-01
End Date: 2034-05-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

250

Intervention / Treatment

Multivessel Hybrid Coronary Revascularization

Off-pump coronary arterial bypass grafting (OPCAB)

Sponsor

Catharina Hospital Eindhoven

Source: clinicaltrials.gov

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Multiparametric MRI Assessment of Atrial Heart Disease as a Predictor of Atrial Fibrillation After Myocardial Revascularization Surgery

Study ID: NCT04657835
Start Date: 2026-03-01
End Date: 2029-03-02
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment

4D cardiac MRI with gadoteric acid

Blood sample

Implantable Loop Recorder (ILR)

Right atrial biopsy

Sponsor

Saint Etienne University Hospital Center

Source: clinicaltrials.gov

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Optimizing Ocular Outcomes: A Dual-armed Study for Periorbital Burn Management

Study ID: NCT06362226
Start Date: 2026-02-28
End Date: 2027-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

10

Intervention / Treatment

Steroid/Antibiotic (Maxitrol)

5-F U/Ken A log

Sponsor

Virginia Commonwealth University

Source: clinicaltrials.gov

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Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Study ID: NCT06333652
Start Date: 2026-03-01
End Date: 2028-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

14

Intervention / Treatment

Ravalizumab

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis

Study ID: NCT06691217
Start Date: 2026-02-16
End Date: 2030-04-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

CANAKINUMAB (ILARIS®)

Saline (NaCl 0,9 %) (placebo)

Sponsor

Massachusetts General Hospital

Source: clinicaltrials.gov

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M-2018-334 in Hematological Malignancies

Study ID: NCT06225050
Start Date: 2026-02-28
End Date: 2029-02-28
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

18

Intervention / Treatment

CliniMACS Prodigy® LP-TCRα/β-19-45RA (Trial Version)

Sponsor

Miltenyi Biomedicine GmbH

Source: clinicaltrials.gov

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