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Clinical trials

4015 results

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A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma

Study ID: NCT07422896
Start Date: 2026-06-01
End Date: 2030-06-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

25

Intervention / Treatment

B-cell vaccination

Sponsor

Catalina Lee Chang

Source: clinicaltrials.gov

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High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe)

Study ID: NCT07223385
Start Date: 2026-04
End Date: 2030-07
Study Type

Interventional

Study Phase

Phase2

No. of Participants

80

Intervention / Treatment

Cardio-Oncology Referral

Notification to PCP/General Cardiologist

Sponsor

Cedars-Sinai Medical Center

Source: clinicaltrials.gov

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A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients With Refractory or Relapsed CLL/SLL

Study ID: NCT06979076
Start Date: 2026-07
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

12

Intervention / Treatment

MS-553, DS1

MS-553, DS2

Sponsor

MingSight Pharmaceuticals, Inc

Source: clinicaltrials.gov

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Phase II Trial of Sacituzumab Tirumotecan in Patients With SMARCB1-Deficient Renal Medullary Carcinoma

Study ID: NCT07438626
Start Date: 2026-06-01
End Date: 2030-02-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

20

Intervention / Treatment

Sacituzumab tirumotecan

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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An Observational Clinical Study on the Association of Intestinal Ruminococcus Gnavus and Its Derived Biogenic Amines With Metabolic Dysfunction-associated Fatty Liver Disease

Study ID: NCT07455149
Start Date: 2026-04-01
End Date: 2030-10-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

observational study, no intervention

Sponsor

ZHujiang hospital

Source: clinicaltrials.gov

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Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse

Study ID: NCT06948084
Start Date: 2026-04-29
End Date: 2028-02-28
Study Type

Interventional

Study Phase

Phase2

No. of Participants

80

Intervention / Treatment

Biospecimen Collection

Bone Marrow Biopsy

Carfilzomib

Computed Tomography

Daratumumab and Recombinant Human Hyaluronidase

Dexamethasone

FDG-Positron Emission Tomography

Pomalidomide

Teclistamab

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Multimodal Radiology Report to Improve Patient-centered Radiology

Study ID: NCT07159438
Start Date: 2026-12
End Date: 2028-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

AI-Generated Video Radiology Report Explanation

Sponsor

Harvard Medical School (HMS and HSDM)

Source: clinicaltrials.gov

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The ECHO Study: Compassion-focused Therapy for Young Voice Hearers and Their Caregivers

Study ID: NCT07314515
Start Date: 2026-06-01
End Date: 2029-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

ECHO Manualized CFT treatment for young voice heares

Sponsor

University of Southern Denmark

Source: clinicaltrials.gov

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Peritumoral and Periganglionic Infiltration of Levobupivacaine Prior to Conservative Surgery for Triple-negative Breast Cancer

Study ID: NCT07458204
Start Date: 2026-10-01
End Date: 2032-10-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

760

Intervention / Treatment

LVB infiltration

Sponsor

Institut Jean-Godinot

Source: clinicaltrials.gov

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Mobile Vehicle-Based Delivery of Lenacapavir PrEP in Los Angeles County

Study ID: NCT07467018
Start Date: 2026-04-07
End Date: 2027-12-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment

Community-based healthcare delivery

lencapavir

Sponsor

University of California, Los Angeles

Source: clinicaltrials.gov

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