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Clinical trials

3917 results

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A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients with Recurrent Malignant Glioma

Study ID: NCT06614855
Start Date: 2026-01-01
End Date: 2028-01-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

12

Intervention / Treatment

Q 134

Q 134

Sponsor

James marked, MD

Source: clinicaltrials.gov

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The Efficacy and Safety of Puerarin in Obesity Treatment

Study ID: NCT06968208
Start Date: 2025-08-01
End Date: 2029-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

80

Intervention / Treatment

Puerarin

Placebo

Sponsor

Ruisin Hospital

Source: clinicaltrials.gov

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Conservative Versus Operative - First Time Shoulder Dislocations

Study ID: NCT05532150
Start Date: 2025-08
End Date: 2032-09
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

Arthroscopic Bankart repair

Physical therapy

Sponsor

Columbia University

Source: clinicaltrials.gov

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DZD8586 Combination Therapy in Patients With Diffuse Large B-cell Lymphoma (TAI-SHAN12)

Study ID: NCT07059650
Start Date: 2025-09
End Date: 2030-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

150

Intervention / Treatment

DZD8586+R-CHOP

DZD8586+R-GemOx

DZD8586+BR

Sponsor

Dizal Pharmaceuticals

Source: clinicaltrials.gov

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BRAVE Study: QL1706 + Bevacizumab + SBRT for BCLC-C HCC With PVTT or Oligometastases

Study ID: NCT07062055
Start Date: 2025-07-25
End Date: 2029-07-25
Study Type

Interventional

Study Phase

Phase2

No. of Participants

46

Intervention / Treatment

Anti-VEGF

Immunotherapy

Local Therapy

Sponsor

Shandong Cancer Hospital and Institute

Source: clinicaltrials.gov

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A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

Study ID: NCT07049055
Start Date: 2025-09
End Date: 2028-09
Study Type

Interventional

Study Phase

Phase2

No. of Participants

144

Intervention / Treatment

E-DV-D682

EDV-GC

Gemcitabine

Nab paclitaxel.

Sponsor

Engeneic Pty Limited

Source: clinicaltrials.gov

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Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke

Study ID: NCT07047014
Start Date: 2025-07-30
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Phase3

No. of Participants

596

Intervention / Treatment

Tenecteplase (0.25mg/kg)

Standard medical treatment

Sponsor

Beijing Tia N-hospital

Source: clinicaltrials.gov

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Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

Study ID: NCT07058155
Start Date: 2025-08-01
End Date: 2034-02-01
Study Type

Interventional

Study Phase

Phase4

No. of Participants

70

Intervention / Treatment

Transjugular Intrahepatic Portosystemic Shunt (TIPS)

Sleeve Gastrectomy

Anti-Obesity Pharmacotherapy (Class Effect)

Lifestyle Counseling - Diet & Physical-Activity Program

Sponsor

The Cleveland Clinic

Source: clinicaltrials.gov

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Evaluation of the Effectiveness of Extending the "Passerelle" System for Prescribing Adapted Physical Activity to Patients With Type 2 Diabetes in Nouvelle-AQUItaine (France)

Study ID: NCT06493955
Start Date: 2025-09
End Date: 2028-09
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

308

Intervention / Treatment

Adapted physical activity for 12 months

Adapted physical activity for 6 months

Sponsor

University Hospital, Bordeaux

Source: clinicaltrials.gov

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Ischemia Detection During Development of Acute Compartment Syndrome

Study ID: NCT06079255
Start Date: 2025-10-15
End Date: 2027-10-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

60

Intervention / Treatment

IscAlert sensor(s) in patient with risk of acute compartment syndrome

Sponsor

Oslo University Hospital

Source: clinicaltrials.gov

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