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NCT07322367 | RECRUITING | Lung Cancer

A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients
Sponsor:

Wake Forest University Health Sciences

Brief Summary:

To evaluate the real-world effectiveness and implementation strategies for mPATH-Lung, investigators propose a pragmatic, randomized controlled trial across an academic Learning Health System. The trial will contrast several approaches to participant outreach and will specifically target engaging fully powered cohorts of racial/ethnic minorities and rural residents.

Condition or disease

Lung Cancer

Intervention/treatment

Portal Message with Reminder Text Messages

Text Message with Reminder Text Messages

Portal message only

Usual Care

Phase

NA

Detailed Description:

Primary Objective: Evaluate the real-world effectiveness of mPATH-Lung in increasing lung cancer screening rates across diverse populations. Secondary Objectives * Compare the differential effectiveness of three outreach strategies for engaging participants with mPATH-Lung across vulnerable rural or ethnic/racial minority population subgroups. * Estimate the additional revenue generated by mPATH-Lung through increased screening and downstream care. * Evaluate the potential for over-screening and the impact of applying HEDIS-based exclusion criteria

Study Type : INTERVENTIONAL
Estimated Enrollment : 27000 participants
Masking : SINGLE
Primary Purpose : SCREENING
Official Title : A Pragmatic Randomized-Controlled Learning Health System Trial
Actual Study Start Date : 2026-03-25
Estimated Primary Completion Date : 2027-01
Estimated Study Completion Date : 2027-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 50 Years to 77 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • Eligible patients will
    • * Meet the Medicare criteria for lung cancer screening, as updated in February 2022:
    • * Age 50 - 77 years
    • * Smoked at least 20 pack years
    • * Current smoker or quit smoking within the past 15 years
    • * Be established with a primary care provider within the Atrium Health Wake Forest Baptist health network (defined as having completed at least 1 primary care appointment in the past 6 months or have completed at least 2 primary care appointments within the past 18 months or being scheduled to see a health network primary care provider within the next 30 days).
    • * Have a patient portal account or cellphone number listed in the electronic health record
    • * Have a North Carolina address listed in the electronic health record
    Exclusion Criteria
    • The following patients will be excluded
      • * Patients flagged as needing a language interpreter in the electronic health record for any language other than Spanish (electronic messages and intervention are deliverable in English or Spanish only)
      • * Those for whom lung cancer screening would be or may be inappropriate
        • electronic health record Prior history of lung cancer electronic health record Chest CT within the last 12 months electronic health record Those meeting the HEDIS COL-E measure exclusion criteria based on significant comorbidities and/or frailty.
A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

Location Details

NCT07322367

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, North Carolina

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States, 27157