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Clinical trials

2615 results

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Daratumumab Versus Rituximab in the Management of Pediatric Primary Immune Thrombocytopenia (ITP)

Study ID: NCT07362238
Start Date: 2026-03
End Date: 2028-03
Study Type

Interventional

Study Phase

Phase2

No. of Participants

122

Intervention / Treatment

Rituximab

daratumumab

Sponsor

Institute of Hematology & Blood Diseases Hospital, China

Source: clinicaltrials.gov

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A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

Study ID: NCT07202546
Start Date: 2026-02-06
End Date: 2028-11-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

550

Intervention / Treatment

VH4524184

Emtricitabine (FTC) and tenofovir alafenamide (TAF) Fixed Dose Combination (FDC) tablets

Dolutegravir / Lamivudine (DTG/3TC)

Sponsor

ViiV Healthcare

Source: clinicaltrials.gov

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AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions

Study ID: NCT06950060
Start Date: 2026-02-14
End Date: 2030-01-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

48

Intervention / Treatment

Moderate-to-high intensity cycling

Low-intensity cycling

Health education session

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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A Study of Propranolol to Treat Kaposi Sarcoma

Study ID: NCT05797662
Start Date: 2026-09
End Date: 2029-04
Study Type

Interventional

Study Phase

Phase2

No. of Participants

25

Intervention / Treatment

Propranolol

Sponsor

AIDS Malignancy Consortium

Source: clinicaltrials.gov

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A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Advanced Squamous Non-Small Cell Lung Cancer

Study ID: NCT07318883
Start Date: 2026-03
End Date: 2031-01
Study Type

Interventional

Study Phase

Phase3

No. of Participants

720

Intervention / Treatment

HLX07

HLX07 placebo

Serplulimab

Pembrolizumab

Carboplatin

Paclitaxel or Nab-Paclitaxel

Sponsor

Shanghai Henlius Biotech

Source: clinicaltrials.gov

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Pulse Oximetry Accuracy by Skin Color

Study ID: NCT05692453
Start Date: 2026-07
End Date: 2027-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

540

Intervention / Treatment

Arterial blood gas with co-oximetry

Sponsor

Brittany Willer

Source: clinicaltrials.gov

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Long-term Effects of Family WISH Program for Adolescents With Congenital Heart Disease

Study ID: NCT06719323
Start Date: 2026-06-01
End Date: 2027-07-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

104

Intervention / Treatment

Family Walking Instruction with Support by Heart (Family WISH) program

Comparison group

Sponsor

χ-wen Chen

Source: clinicaltrials.gov

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Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas

Study ID: NCT07293403
Start Date: 2026-06-07
End Date: 2027-11-23
Study Type

Interventional

Study Phase

Phase2

No. of Participants

25

Intervention / Treatment

Biospecimen Collection

Bone Marrow Aspiration

Bone Marrow Biopsy

Computed Tomography

Duvelisib

Positron Emission Tomography

Survey Administration

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421-T1 and DW4421S-T1 in Healthy Adult Volunteers

Study ID: NCT07364851
Start Date: 2026-03-06
End Date: 2026-08-30
Study Type

Interventional

Study Phase

Phase1

No. of Participants

38

Intervention / Treatment

DW4421-T1

DW4421S-T1

Sponsor

Daewon Pharmaceutical Co., Ltd.

Source: clinicaltrials.gov

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A Study of TAK-226 for Transfusion-Dependent Anemia in Japanese Patients With Lower-Risk Myelodysplastic Syndromes

Study ID: NCT07319845
Start Date: 2026-02-06
End Date: 2033-01-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

27

Intervention / Treatment

TAK-226

Sponsor

Takeda

Source: clinicaltrials.gov

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