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Clinical trials

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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

Study ID: NCT06976203
Start Date: 2025-07-25
End Date: 2029-02-23
Study Type

Interventional

Study Phase

Phase3

No. of Participants

586

Intervention / Treatment

Karxt

KarX-EC

Placebo

Sponsor

Bristol-Myers Squibb

Source: clinicaltrials.gov

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Neuropathic Pain Intervention With tDCS in Brazilian Military Personnel (NeuBRAIN Trial)

Study ID: NCT06994390
Start Date: 2026-03-01
End Date: 2030-03-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment

tDCS

sham intervention

Sponsor

Goiás Military Police Hospital

Source: clinicaltrials.gov

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Identification of Anti-HIF 1alpha Autoantibodies in Patients with Anorexia Nervosa and Characterization of Their Pathogenic Potential in Undernutrition-associated Hepatic Cytolysis

Study ID: NCT06869590
Start Date: 2025-09-01
End Date: 2028-09-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

250

Intervention / Treatment

blood sampling

blood sampling after 3-4 months

Sponsor

Public assistance Hospitals in Marseille

Source: clinicaltrials.gov

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A Novel Psychological Intervention for Adults With Bipolar Disorder and Attention Deficit Hyperactivity Disorder Comorbidity (VECTOR)

Study ID: NCT07039903
Start Date: 2025-09-01
End Date: 2027-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

68

Intervention / Treatment

Cognitive behavioral therapy (CBT) + Functional Remediation (FR)

Sponsor

Vall d'Hebron Research Institute University Hospital

Source: clinicaltrials.gov

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BRAZAN Trial in Frontline MCL

Study ID: NCT06854003
Start Date: 2025-08
End Date: 2039-11-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

Bendemustine

Rituximab

Cytarabine

Zanubrutinib

Sonrotoclax

Sponsor

Christine Ryan

Source: clinicaltrials.gov

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Prospective Cohort of Patients Treated Using Neoadjuvant Modified FOLFIRINOX 6 Cycles for Potentially Resectable Pancreatic Duct Adenocarcinoma, Candidate for Participation in the PANACHE02 Clinical Trial

Study ID: NCT07034703
Start Date: 2025-09
End Date: 2032-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

820

Intervention / Treatment
Sponsor

University Hospital, Rouen

Source: clinicaltrials.gov

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Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation

Study ID: NCT06908590
Start Date: 2025-08-01
End Date: 2027-07-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

50

Intervention / Treatment

Education, Providing and Engaging Social Support and Assistance with Health System Navigation

Sponsor

Johns Hopkins University

Source: clinicaltrials.gov

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Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial

Study ID: NCT06850090
Start Date: 2025-07-30
End Date: 2028-06
Study Type

Interventional

Study Phase

Phase3

No. of Participants

210

Intervention / Treatment

Tas-102

Capecitabine

Sponsor

Shandong Cancer Hospital and Institute

Source: clinicaltrials.gov

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Neoadjuvant Darovasertib in Primary Uveal Melanoma

Study ID: NCT07015190
Start Date: 2025-09-30
End Date: 2027-12-07
Study Type

Interventional

Study Phase

Phase3

No. of Participants

520

Intervention / Treatment

Incomes

Primary Local Therapy

Sponsor

IDEAYA Biosciences

Source: clinicaltrials.gov

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Evaluating a Personalised Online Program With Human Support for Women With Depression and Its Impact on Mental Health and Biological Changes

Study ID: NCT07060690
Start Date: 2026-01
End Date: 2027-08
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment

iCBT with human interaction

Psychoeducational videos

Sponsor

Francesc Colom, Psyd, Phd

Source: clinicaltrials.gov

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