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Clinical trials

2615 results

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A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)

Study ID: NCT07282574
Start Date: 2026-02-28
End Date: 2030-05-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

360

Intervention / Treatment

Spirituality 489

Ocrelizumab

Placebo

Sponsor

Hoffmann-La Roche

Source: clinicaltrials.gov

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AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Study ID: NCT07368959
Start Date: 2026-05
End Date: 2028-01
Study Type

Interventional

Study Phase

Phase3

No. of Participants

120

Intervention / Treatment

Combination Product: AURN001 + Y-27632

Placebo

Sponsor

Aurion Biotech

Source: clinicaltrials.gov

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Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery

Study ID: NCT07108582
Start Date: 2026-04-01
End Date: 2028-07-01
Study Type

Interventional

Study Phase

Phase3

No. of Participants

270

Intervention / Treatment

no NSAID

protocol for administering NSAIDs already used in routine care

Sponsor

University Hospital, Strasbourg, France

Source: clinicaltrials.gov

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The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans

Study ID: NCT06746727
Start Date: 2028-07-03
End Date: 2030-09-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

29

Intervention / Treatment

Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)

Sponsor

VA Office of Research and Development

Source: clinicaltrials.gov

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Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket Trial

Study ID: NCT06381661
Start Date: 2026-05-01
End Date: 2031-05-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

2000

Intervention / Treatment

Tocilizumab

Baricitinib

Anakinra

Hydrocortisone

Hydrocortisone and fludrocortisone

Heparin

Low molecular weight heparin

Recombinant humanThrombomodulin( rhTM)

You brush

Usual care

blood purification with MTx.100 Plasma Adsorption Column

G-CSF filgrastim

Interferon gamma-1b

Fludrocortisone

Prophylactic unfractionated heparin (UFH)

Octaplas LG

Plasminogen

Sponsor

Public Assistance - Paris Hospitals

Source: clinicaltrials.gov

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How to Develop the Highest Possible Leading-edge Interdisciplinary Care Model for People With MS, That Will be Relevant to All Stakeholders and Declinable to Different Local Contexts With the Ultimate Goal of Ensuring the Highest Level of Quality of Care in MS.

Study ID: NCT07289724
Start Date: 2026-03
End Date: 2026-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

57

Intervention / Treatment

Focus group

individual interview

Sponsor

Public Assistance - Paris Hospitals

Source: clinicaltrials.gov

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Crisaborole 2% Versus Tacrolimus 0.1% in Children With Mild to Moderate Atopic Dermatitis

Study ID: NCT07162896
Start Date: 2026-06
End Date: 2027-06
Study Type

Interventional

Study Phase

Phase3

No. of Participants

66

Intervention / Treatment

Crisaborole 2%

Tacrolimus 0.1%

Sponsor

Shalamar Institute of Health Sciences

Source: clinicaltrials.gov

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Versius Clinical Study in Robot Assisted Inguinal Hernia Repair Surgery

Study ID: NCT07316517
Start Date: 2026-03
End Date: 2026-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

30

Intervention / Treatment

Versius Surgical System

Sponsor

CMR Surgical Ltd

Source: clinicaltrials.gov

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Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML

Study ID: NCT07355335
Start Date: 2026-07-09
End Date: 2028-01-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

24

Intervention / Treatment

Ziftomenib

Mezigdomide

Sponsor

Massachusetts General Hospital

Source: clinicaltrials.gov

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Improving Cervical Cancer Prevention Among Women Living With Chronic Conditions.

Study ID: NCT07351110
Start Date: 2026-03-15
End Date: 2026-12-24
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

patient navigation and self-collection

Sponsor

University of Florida

Source: clinicaltrials.gov

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