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Clinical trials

3358 results

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ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)

Study ID: NCT06951646
Start Date: 2025-06-01
End Date: 2030-06-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

70

Intervention / Treatment

Ivonescimab plus docetaxel

Standard Treatment

Sponsor

Second Xiangya Hospital of Central South University

Source: clinicaltrials.gov

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Structured Light Plethysmography Against Standard of Care in the Diagnosis and Monitoring of Dysfunctional Breathing

Study ID: NCT04255446
Start Date: 2025-10
End Date: 2026-10
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

60

Intervention / Treatment

Thora3DiTM

Sponsor

Pneumacare Ltd

Source: clinicaltrials.gov

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Is Intraoperative PTH Monitoring Obsolete in Times of Choline PET/CT? a Prospective Multicenter Cohort Study to Determine Whether the Regular Preoperative Use of Choline-PET/CT Scan Obviate the Need for Intraoperative PTH-measurement in Patients with Primary Hyperparathyreoidism

Study ID: NCT06804681
Start Date: 2025-09
End Date: 2028-09
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

1000

Intervention / Treatment
Sponsor

University of Zurich

Source: clinicaltrials.gov

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A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations

Study ID: NCT06019481
Start Date: 2025-06-30
End Date: 2030-06-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment
Sponsor

Regeneron Pharmaceuticals

Source: clinicaltrials.gov

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Establishment and Clinical Application of AI-based Multimodal Diagnosis System for Ovarian Tumors

Study ID: NCT06703112
Start Date: 2025-06-01
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

584

Intervention / Treatment

An auxiliary diagnostic model for ovarian tumors

Sponsor

Beijing Shijitan Hospital, Capital Medical University

Source: clinicaltrials.gov

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Chemoimmunotherapy With or Without SBRT Before Surgery for Locally Advanced Oral and Oropharyngeal Cancer

Study ID: NCT06861712
Start Date: 2025-05-06
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

50

Intervention / Treatment

SBRT

Docetaxel, Cisplatin, Toripalimab

Radical resection surgery

IMRT ± chemotherapy/toripalimab

Sponsor

Sun Yat-sen University

Source: clinicaltrials.gov

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Effect of STRAIN COUNTER-STRAIN ON PATIENTS WITH ANKLE SPRAINS

Study ID: NCT06954012
Start Date: 2025-08-01
End Date: 2026-03-28
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

36

Intervention / Treatment

EXERCISE TRAINING WITH OR WITHOUT MEDICATION

Exercise

Sponsor

Al-ahliyya amman university

Source: clinicaltrials.gov

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Implementation of Team Clinic for Type 2 Diabetes (TCT2)

Study ID: NCT06923046
Start Date: 2025-07-01
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

160

Intervention / Treatment

Standard of Care

Shared Medical Appointments

Sponsor

Children's Hospital Los Angeles

Source: clinicaltrials.gov

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Exploring the Effect of Mindfulness on Quality of Life (QoL) in Spinal Cord Injury (SCI)

Study ID: NCT06003712
Start Date: 2025-08-01
End Date: 2025-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

10

Intervention / Treatment

Mindfulness

Sponsor

University of Miami

Source: clinicaltrials.gov

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Sleep Disturbances in Surgical Patients With GI Cancers: A Quantitative and Qualitative Analysis

Study ID: NCT05044312
Start Date: 2025-09-30
End Date: 2026-12-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

Sleeping Disturbances

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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