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Clinical trials

3365 results

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Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

Study ID: NCT06954831
Start Date: 2025-10-05
End Date: 2026-03-24
Study Type

Interventional

Study Phase

Phase2

No. of Participants

82

Intervention / Treatment

Cone-Beam Computed Tomography

Hypofractionated External Beam Radiation Therapy

Administration questionnaire

Radiation Boost

Whole Breast Irradiation

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

Study ID: NCT06710431
Start Date: 2025-10-01
End Date: 2027-12-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

36

Intervention / Treatment

AFA-281

Sponsor

Afasci Inc

Source: clinicaltrials.gov

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Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Study ID: NCT06943573
Start Date: 2025-06
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase3

No. of Participants

90

Intervention / Treatment

psilocybin (25 mg)

psilocybin 1mg micro-dose

Sponsor

Lakshmi n yatham

Source: clinicaltrials.gov

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Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

Study ID: NCT06727773
Start Date: 2025-06
End Date: 2028-10-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

90

Intervention / Treatment

Memantine

Placebo medication

Exercise Intervention

Exercise Control

Sponsor

UNC Lineberger Comprehensive Cancer Center

Source: clinicaltrials.gov

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Metabolite Changes Following Consumption Of Different Protein Drinks In Singapore Older Adults

Study ID: NCT06956131
Start Date: 2025-05-29
End Date: 2025-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

32

Intervention / Treatment

Casein Protein Isolate Drink

Whey Protein Isolate Drink

Soy Protein Isolate Drink

Maltodextrin Drink

Sponsor

National University of Singapore

Source: clinicaltrials.gov

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Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients With Minimal Residual Disease

Study ID: NCT06878131
Start Date: 2025-09-30
End Date: 2028-12-22
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

Colorectal Cancer

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Study ID: NCT05253131
Start Date: 2025-06-15
End Date: 2031-06-15
Study Type

Interventional

Study Phase

Phase2

No. of Participants

41

Intervention / Treatment

Selumetinib

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Expanding Access to Cervical Cancer Screening Through Primary HR-HPV Testing and Self-sampling: a Multicomponent Intervention for Safety Net Health Systems

Study ID: NCT06843720
Start Date: 2025-08-31
End Date: 2031-03-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

7100

Intervention / Treatment
Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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The Prevalence, Disease Burden and Prognosis of COPD in Patients With Cardiovascular Diseases

Study ID: NCT06909773
Start Date: 2025-05-31
End Date: 2026-02-28
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

3000

Intervention / Treatment

Guideline education and implementation intervention

Sponsor

AstraZeneca

Source: clinicaltrials.gov

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Optimizing Suicide Prevention Strategies for Pediatric Primary Care

Study ID: NCT06194331
Start Date: 2025-06-01
End Date: 2026-05-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

60

Intervention / Treatment

iCHART/cASAP

Treatment as usual

Sponsor

University of Pittsburgh

Source: clinicaltrials.gov

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