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Clinical trials

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Investigation of the Effect on Ocular Health and Visual Quality With Corneal and Scleral RGP Lenses in Patients With Keratoconus

Study ID: NCT06921967
Start Date: 2025-06
End Date: 2028-02-29
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

50

Intervention / Treatment

Rose K2

Onefit with

Sponsor

University of Aarhus

Source: clinicaltrials.gov

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A Portable Thoracic Impedance Device for Detecting Pulmonary Congestion in Heart Failure Patients

Study ID: NCT06604468
Start Date: 2025-06-01
End Date: 2026-05-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

30

Intervention / Treatment

Thoracic bioimpedance tomography

Sponsor

University of Montreal Hospital Center (CHUM)

Source: clinicaltrials.gov

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Non-invasive VNS for PD Gait

Study ID: NCT06562569
Start Date: 2025-05-27
End Date: 2027-04-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

non-invasive cervical vagal nerve stimulation ncVNS

Sponsor

VA Office of Research and Development

Source: clinicaltrials.gov

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Genetic Ablation of CD33 in HSC to Broaden the Therapeutic Index of CD33-directed Immunotherapy in Patients with AML

Study ID: NCT05662904
Start Date: 2028-01
End Date: 2030-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

12

Intervention / Treatment

Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion

Gemtuzumab ozogamicin

Sponsor

German Cancer Research Center

Source: clinicaltrials.gov

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Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.

Study ID: NCT06899204
Start Date: 2025-05-15
End Date: 2026-08-17
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

150

Intervention / Treatment

Abrocitinib

Sponsor

Pfizer

Source: clinicaltrials.gov

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Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma

Study ID: NCT06858501
Start Date: 2025-06-20
End Date: 2028-12-20
Study Type

Interventional

Study Phase

Phase2

No. of Participants

84

Intervention / Treatment

Biospecimen Collection

Computed Tomography

Florbenguane F18

Magnetic Resonance Imaging

Positron Emission Tomography

Administration questionnaire

Sponsor

Children's Oncology Group

Source: clinicaltrials.gov

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Understanding Decentralized Trial Engagement and Clinical Impediments Through Digital Efforts (UDECIDE) Among Unrepresented Groups With Poor Cardiovascular and Cardiometabolic Health

Study ID: NCT06587204
Start Date: 2025-09-20
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

125

Intervention / Treatment

Control Group

Decentralized Group

Digital Literacy Navigation Group

Social Care Navigation Group

Sponsor

University of Miami

Source: clinicaltrials.gov

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Pre-surgical Tirzepatide-assisted Weight Loss in Men with Diabetes and Prostate Cancer: a Pilot Feasibility Study

Study ID: NCT06759701
Start Date: 2025-06-30
End Date: 2028-12-31
Study Type

Interventional

Study Phase

Early_phase1

No. of Participants

30

Intervention / Treatment

Tirzepatide

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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The Utilization of a Shoe Insert on Individuals with Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, Biomechanics, and Pain Intensity

Study ID: NCT06891001
Start Date: 2025-06-01
End Date: 2027-01-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

36

Intervention / Treatment

Unilateral neutral shoe insert

Bilateral Shoe Insert

Physical Therapy

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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Effects of tDCS on Motor Cortex During ACL Recovery

Study ID: NCT06818201
Start Date: 2025-05-22
End Date: 2026-12-22
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

54

Intervention / Treatment

NIBS

Rehabilitation

Sham Comparator

Sponsor

Catholic University Foundation of Valencia San Vicente Mártir

Source: clinicaltrials.gov

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