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NCT07180849 | RECRUITING | Dental Plaque Accumulation

Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
Sponsor:

Pakistan Institute of Medical Sciences

Information provided by (Responsible Party):

Afifa Fahim

Brief Summary:

In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.

Condition or disease

Dental Plaque Accumulation

Nanoparticles

Fluoride Varnishes

Intervention/treatment

Fluoride varnish

Novel titania nanoparticle infused fluoride varnish

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 20 participants
Masking : QUADRUPLE
Primary Purpose : PREVENTION
Official Title : Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial.
Actual Study Start Date : 2025-11
Estimated Primary Completion Date : 2027-07
Estimated Study Completion Date : 2027-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 16 Years to 30 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion criteria
  • * Patients planned for fixed orthodontic treatment.
  • * Patients within age group 16-30 years.
  • * Patient with no history of previous orthodontic treatment.
  • * Patients with no active periodontal diseases.
  • Exclusion criteria
    • * Patient undergoing any antibiotic therapy.
    • * Patients with any craniofacial abnormality.
    • * Patient with mixed dentition
Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.

Location Details

NCT07180849

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Locations

RECRUITING

Pakistan,

Pakistan Institute of Medical Sciences

Islamabad, Pakistan,