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NCT07140757 | RECRUITING | Low Risk

Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
Sponsor:

M.D. Anderson Cancer Center

Brief Summary:

To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.

Condition or disease

Low Risk

Papillary Thyroid Cancer

Radiofrequency Ablation

Intervention/treatment

Questionnaire

Detailed Description:

Primary Objectives • To evaluate thyroid nodule volume changes over time in participants undergoing RFA as part of clinical care Secondary Objectives * To establish the health-related quality of life among participants undergoing with ultrasound guided RFA. * To evaluate the sonographic features of thyroid nodules over time following ultrasound guided RFA. * To assess adverse events rates following ultrasound guided RFA.

Study Type : OBSERVATIONAL
Estimated Enrollment : 50 participants
Official Title : Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
Actual Study Start Date : 2026-02-04
Estimated Primary Completion Date : 2028-12-31
Estimated Study Completion Date : 2030-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Eligibility Criteria
  • 1. Participants scheduled to undergo ultrasound-guided RFA for the following conditions: benign thyroid nodules, indeterminate thyroid nodules, low-risk DTC, and recurrent PTC
  • 2. Participant is over 18 years and is either not a surgical candidate or has declined surgery.
  • 3. Capable and willing to provide written informed consent
  • 4. Participant has one of the following diagnoses
    • * Biopsy-proven benign thyroid nodules causing compressive and/or cosmetic symptoms who are requesting treatment,
    • * Biopsy-proven indeterminate nodules (AUS or follicular neoplasm)
    • * Papillary thyroid carcinoma (PTC) without metastasis
    • * Locally recurrent thyroid cancer (\< 2 cm).
    Exclusion Criteria
  • 1. Participants meeting any of the following criteria will be excluded:
  • 2. Participants considered unsuitable for RFA by the treating physician
    • Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers

    Location Details

    NCT07140757

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    How to Participate

    Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

    Locations

    RECRUITING

    United States, Texas

    MD Anderson Cancer Center

    Houston, Texas, United States, 77030