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NCT07137286 | RECRUITING | LDL Hyper-responsiveness

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet
Sponsor:

Mayo Clinic

Information provided by (Responsible Party):

Stephen L. Kopecky

Brief Summary:

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.

Condition or disease

LDL Hyper-responsiveness

Study Type : OBSERVATIONAL
Estimated Enrollment : 100 participants
Official Title : Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet
Actual Study Start Date : 2025-10
Estimated Primary Completion Date : 2027-08
Estimated Study Completion Date : 2027-08

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * 18 years of age or older
  • * LDL-C \>170 mg/dL in response to starting a ketogenic diet
Exclusion Criteria
  • * Patients who do not consent to blood draw for genetic testing
  • * Those with LDL-C \<170 mg/dL on a ketogenic diet
A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Location Details

NCT07137286

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Minnesota

Mayo Clinic

Rochester, Minnesota, United States, 55905