University of California, Los Angeles
John N. Mafi, MD, MPH
The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority. This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.
Prescribing Patterns, Physician
Physician's Practice Patterns
Drug Utilization Review
Algorithmic Defaulting (Indication-Based Default)
Active Physician Choice
NA
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 372 participants |
| Masking : | DOUBLE |
| Primary Purpose : | HEALTH_SERVICES_RESEARCH |
| Official Title : | Quality Improvement Initiative Leveraging Electronic Healthcare Records to Reduce Inappropriate Proton Pump Inhibitors (PPI) Prescribing at UCLA. |
| Actual Study Start Date : | 2026-01 |
| Estimated Primary Completion Date : | 2026-11 |
| Estimated Study Completion Date : | 2027-01 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 50 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
UCLA Health System
Los Angeles, California, United States, 90024