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NCT06930976 | RECRUITING | Glucose

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells
Sponsor:

Vanderbilt University Medical Center

Information provided by (Responsible Party):

Matthew Stier

Brief Summary:

The purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours and collect immune cells from the blood to track uptake and usage of this glucose within these immune cells.

Condition or disease

Glucose

Metabolism

Isotope Labeling

Immune System and Related Disorders

Intervention/treatment

13C6-Glucose

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 12 participants
Masking : NONE
Primary Purpose : BASIC_SCIENCE
Official Title : Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells
Actual Study Start Date : 2025-10-01
Estimated Primary Completion Date : 2027-06-30
Estimated Study Completion Date : 2027-06-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Adults aged 18 or older
Exclusion Criteria
  • * Pregnant
  • * Prisoner or in police custody
  • * Uncontrolled hyperglycemia/diabetes
  • * Current participation in another study where the total volume of blood drawn, when added to this study blood draw volume, exceeds 500cc in an 8 week period
  • * Any medical issue or pharmacologic exposure which, in the opinion of the study investigator, that might interfere with the study objectives
  • * Any reason which, in the opinion of the study investigator, adds additional risk to the participant
Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Location Details

NCT06930976

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How to Participate

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Locations

RECRUITING

United States, Tennessee

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37212