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NCT06333652 | RECRUITING | Preeclampsia

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
Sponsor:

Mayo Clinic

Information provided by (Responsible Party):

Maria Lourdes Gonzalez Suarez

Brief Summary:

The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome.

Condition or disease

Preeclampsia

Intervention/treatment

Ravulizumab

Phase

PHASE2

Study Type : INTERVENTIONAL
Estimated Enrollment : 14 participants
Masking : NONE
Primary Purpose : TREATMENT
Official Title : Clinical Trial on the Use of Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
Actual Study Start Date : 2026-03-01
Estimated Primary Completion Date : 2026-12-31
Estimated Study Completion Date : 2028-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 50 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Individuals with \< 34 0/7 weeks of gestation.
  • * Individuals with severe preeclampsia or HELLP features.
Exclusion Criteria
  • * Pregnant female patients presenting with disseminated intravascular coagulopathy (DIC).
  • * Individuals with non-reassuring fetal status requiring delivery, non-viable fetuses, previable pregnancy (\<23 0/7 weeks gestation), stroke, in utero fetal demise, known atypical hemolytic uremic syndrome, familial or acquired thrombocytopenia purpura, paroxysmal nocturnal hemoglobinuria, allergy to Ravulizumab, inability or unwillingness to sign informed consent.
Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Location Details

NCT06333652

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Minnesota

Mayo Clinic Minnesota

Rochester, Minnesota, United States, 55905