Johns Hopkins University
The investigators will test the hypothesis that images of the optic nerve head taken a 2 different eye pressures will yield strain estimates that are predictive of the course of glaucoma.
Glaucoma, Open-Angle
Images of eye at 2 eye pressures
NA
Existing glaucoma patients and suitable control adults will be imaged with an FDA-approved optical coherence tomography instrument. Those who are imaged at 2 different eye pressures will generate biomechanical strain estimates. These will be compared to visual field and retinal nerve fiber layer measurements over time. The investigators expect that baseline strain and their changes over time will be associated with progression rate of glaucoma damage, providing a biomarker for susceptibility.
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 130 participants |
| Masking : | NONE |
| Primary Purpose : | DIAGNOSTIC |
| Official Title : | Optic Nerve Head Strain as Biomarker for Glaucoma |
| Actual Study Start Date : | 2024-07-01 |
| Estimated Primary Completion Date : | 2028-01-31 |
| Estimated Study Completion Date : | 2028-01-31 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years to 90 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
Johns Hopkins University
Baltimore, Maryland, United States, 21287