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NCT05924529 | RECRUITING | Alzheimer's Disease and Related Dementia


Alzheimer's Disease and Related Dementias (ADRD) Prevalence in American Samoa
Sponsor:

American Samoa Community Cancer Coalition

Brief Summary:

The goal of this study is to learn about ADRD prevalence within the Samoan population. Participants will be administered a series of cognitive assessments to determine cognitive status and a population-based prevalence of Mild Cognitive Impairment (MCI) and ADRD. Blood samples will also be collected from the participants for genetic and plasma biomarker analysis.

Condition or disease

Alzheimer's Disease and Related Dementia

Detailed Description:

This study aims to do the following: Test ADRD knowledge, health literacy, research readiness and determine ADRD resilience and vulnerability factors, and cognitive status in a probability sample of 981 Samoans age 50+ using culturally adapted instruments in our probability sample. Conduct Gold Standard evaluations in our probability sample using the Uniform Data Set (UDSv3.0) from the National Institute on Aging (NIA) Alzheimer's Disease Research Center program to determine a population-based prevalence of MCI and ADRD for harmonization, data sharing, and comparison to other groups, and, Cross-validate Gold Standard dementia evaluations with genetic (i.e., ApoE) and plasma Amyloid-Tau-Neuronal Injury/Neurodegeneration (ATN) framework biomarkers in our probability sample and compare to information available for other racial/ethnic groups.

Study Type : OBSERVATIONAL
Estimated Enrollment : 1098 participants
Official Title : ADRD Prevalence in American Samoa
Actual Study Start Date : 2022-09-30
Estimated Primary Completion Date : 2025-09
Estimated Study Completion Date : 2025-09

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 50 Years
Sexes Eligible for Study: ALL
Criteria
Inclusion Criteria
  • * Age 50 or older
  • * Community dwelling
  • * Speaks English or Samoan
  • * Willing to contribute a biomarker specimen
Exclusion Criteria
  • * Residing in Assistant Living or Skilled Nursing Facility
  • * Axis 1 Psychiatric diagnosis (e.g., Schizophrenia, Bipolar)
  • * Unstable medical condition (i.e., metastatic cancer) that could preclude completion of study visit

Alzheimer's Disease and Related Dementias (ADRD) Prevalence in American Samoa

Location Details

NCT05924529


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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

American Samoa,

Malaloa GHC Reid Building

Payment payment, American Samoa, 96799

RECRUITING

American Samoa,

Correct Building

Payment payment, American Samoa, 96799

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