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NCT05403177 | RECRUITING | Breast Cancer

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)
Sponsor:

University Health Network, Toronto

Brief Summary:

The Marathon of Hope Cancer Centres Network (MOHCCN) is a national network of cancer centres that pursue collaborative cancer research in precision medicine (an emerging approach for disease treatment and prevention that considers individual variability in DNA, environment and lifestyle) to accelerate the discovery of innovations and improve the health outcomes for cancer patients

Condition or disease

Breast Cancer

Colorectal Cancer

Pancreas Cancer

Kidney Cancer

Prostate Cancer

Ovary Cancer

Head and Neck Cancer

Leukemia

Lymphoma

Lung Cancer

Melanoma

Solid Tumor

Detailed Description:

The purpose of this study is to use evolving technologies such as genomics and artificial intelligence to study cancer so that the right treatment can be given to the right patient, at the right time. Approximately 15,000 participants will take part in the greater MOHCCN study across Canada in the first 5 years, and ultimately the goal is to enroll up to 100,000 over next 10 years.

Study Type : OBSERVATIONAL
Estimated Enrollment : 500 participants
Official Title : Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)
Actual Study Start Date : 2022-06-23
Estimated Primary Completion Date : 2026-10
Estimated Study Completion Date : 2026-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. Patients with histological and/or cytological confirmation of blood or solid tumor malignancies. For tumour types where pre-surgical biopsy is not routinely performed to confirm a pathologic diagnosis of cancer, patients may consent to this protocol, but eligibility must be confirmed after pathology is finalized demonstrating presence of malignancy
  • 2. All patients must be able to satisfy the required minimum data elements for the 15k gold standard cohort through
    • 1. Already existing data that satisfies the minimal requirements of a gold standard case (refer to Table 1)
    • 2. Have sufficient biospecimens (tumor and/or blood samples) available for more comprehensive molecular and immunophenotypic characterization
    • 3. Patients who do not satisfy the required minimum data elements but would like to participate, maybe requested to donate blood and undergo a fresh biopsy if the archived Formalin-fixed paraffin-embedded (FFPE) samples are not available, or in cases where a fresh tumor biopsy is deemed necessary for molecular profiling.
    • 4. Participating patients must agree to share their anonymized clinical and genomic data
    Exclusion Criteria
    • None.
Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Location Details

NCT05403177

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

Canada, Ontario

Kingston Health Sciences Centre

Kingston, Ontario, Canada, Pale eyeliner

NOT YET RECRUITING

Canada, Ontario

Ottawa Health Research Institute

Ottawa, Ontario, Canada, K1Y 4E9

RECRUITING

Canada, Ontario

Princess Margaret Cancer Centre

Toronto, Ontario, Canada, M5G2M9