Epidemiological Surveillance Fungal Infections Malignant Hemopathies
LIVIO PAGANO
The overall purpose of this project is to better understand the epidemiology of COVID-19 in patients with hematological malignancies (including hematopoietic stem cell transplant recipients) in the different European Countries. The results obtained will allow us to better know the prevalence of this complication in the different categories of patients with hematological malignancies (HMs). In order to attain the objectives previously described we will develop a multicentre, international, observational, retrospective and prospective study of consecutive cases of COVID-19 among HMs. There will be a clinical follow-up of the patients included in this study to observe the survival rate. Data collected form this study will be evaluated with a descriptive analysis.
COVID-19 Infection in Hematological Malignancies Patients
At the moment, few data on the epidemiology of SARS-CoV-2 infection in patients suffering from hematological malignancies are available. However, the COVID-19 pandemic presents unique challenges and opportunities on hematological malignancies. The future trajectory of this pandemic appears to be growing and hematology communities must continue to prepare for its spread In this project, we will implement cooperation between all members of the hematology departments both within the EHA and outside it, in order to evaluate the epidemiological data on the incidence and outcome in patients with hematological malignancies infected with SARS-CoV-2. We will provide useful information to inform the individualized plan for patients with hematological malignancies. We aim to evaluate the epidemiology and outcomes of patients with HM infected with COVID-19,estimate the incidence and type of disease, assess the acute and long-term mortality rate and estimate the overall mortality rate of cases. This is a cohort retrospective/prospective survey. In the retrospective phase of the study, participating centers will retrospectively review episodes of COVID-19 disease that occurred in patients with hematological malignancies identified at their institutions from February 2020 to December 2020. In the prospective phase of the study, the researchers will include episodes of COVID-19 disease from the start of the study through December 31, 2021. The study population will need to be over 18 with hematological malignancies and SARS-CoV-2 An electronic database with anonymization will be created and available to collect all information with single access for each participating institution. The data collected will be demographic data,epidemiological factors, admission information, COVID-19 disease severity, history of hematological malignancies, disease status with past / current treatments, and 30 days of diagnosis.
| Study Type : | OBSERVATIONAL |
| Estimated Enrollment : | 3000 participants |
| Official Title : | Epidemiology of COVID-19 Infection in Patients With Hematological Malignancies: A European Haematology Association Survey |
| Actual Study Start Date : | 2020-03-01 |
| Estimated Primary Completion Date : | 2022-09-30 |
| Estimated Study Completion Date : | 2025-12-31 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years to 99 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
ASST-Civil Hospitals
Brescia, Italy,
RECRUITING
AOU Federico II Polyclinic
Naples, Italy,
RECRUITING
Policlinico A. Gemelli IRCCS Foundation
Rome, Italy,
RECRUITING
National Cancer Institute Regina Elena IFO
Rome, Italy,
RECRUITING
Hospital. of Circolo-Fondazione Macchi
Varese, Italy,
RECRUITING
AYES Verona
Verona, Italy,