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NCT00064870 | RECRUITING | Alzheimer Disease


Alzheimer's Disease Genetics Study
Sponsor:

Indiana University

Information provided by (Responsible Party):

Tatiana Foroud

Brief Summary:

The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying and collecting genetic material from families with multiple members diagnosed with AD or dementia.

Condition or disease

Alzheimer Disease

Late Onset Alzheimer Disease

Dementia

Detailed Description:

The purpose of the Alzheimer's Disease Genetics Study is to help identify the genes that may be responsible for causing Alzheimer's Disease (AD) by collecting genetic material from families with multiple members diagnosed with AD. Qualifying families will have two living blood-related individuals who have been diagnosed with or are showing symptoms of AD or dementia. Local study sites are located all over the United States, and arrangements may be made for eligible families who do not live near a participating site. The biological samples and data from these families will be made available to qualified researchers, who must sign a Materials Transfer Agreement (MTA) in order to protect the privacy rights of study participants before receiving samples and data.

Study Type : OBSERVATIONAL
Estimated Enrollment : 10000 participants
Official Title : National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)
Actual Study Start Date : 2002-06
Estimated Primary Completion Date : 2026-07
Estimated Study Completion Date : 2026-07

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Two living family members diagnosed with AD or other dementia with any age of onset
  • * Biological samples available
  • * Fresh blood, or
  • * Immortalized lymphoblastic cell lines, or
  • * 3-5 grams of frozen cerebral cortex; fixed samples are not accepted
  • Please note: this study does not include genetic counseling; because no personal identifying information such as name or date of birth is attached to samples, results of individual tests are not available to participants or family members.
Exclusion Criteria
  • * Does not meet inclusion criteria
  • * Member of a family that was included in the National Institute of Mental Health AD Genetics Sib Pair collection

Alzheimer's Disease Genetics Study

Location Details

NCT00064870


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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

United States, Indiana

Participants are being recruited from all over the United States

Nationwide, Indiana, United States, 46202

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